To maximize the drugability potential, we target approaches to improve clinical benefits based on reverse translational science and emerging biology of the tumor microenvironment.
(Reverse)Translational Science
Identification of patients' unmet needs, novel targets, pathways, and mechanisms.
Drug Discovery & Development
Validation of target, mechanism of action, and proof of concept, and development of novel engager with high potency and good safety profile.
Immunotherapy
Boosting of anti-tumor immunity to fight against cancer.
Direct engagement of myeloid cells with target cells.
Activation of killing mechanism (such as phagocytosis) by myeloid cells directed towards target cells.
Stimulation of myeloid cells to release minimal cytokines and chemokines known to reprogram and reset the immunosuppressive tumor microenvironment and enhance cytotoxic T cell function.
Cross presentation of tumor neoantigens and activation of tumor-specific T cells to support durable anti-tumor immune responses and immunological memory.
First-in-human trial evaluates LTZ's second asset, a first-in-class bispecific myeloid engager targeting EpCAM, a tumor marker highly expressed in a wide range of cancers
General Inquiries
info@ltztherapeutics.comBusiness Development
vivian.tian@ltztherapeutics.comRedwood City, USA
1100 Island Dr., Suite 103, Redwood City, CA, 94065Shenzhen, China
Room 3004, Building B, New Building of Research Institute of Tsinghua University in Shenzhen, Yuehai Sub-district, High-tech Zone Community, Gaoxin South 39th Road, Nanshan District, Shenzhen 518057@ 2026 LTZ Therapeutics Inc., All Rights Reserved.
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